The WHI diet: Difficult to digest

A Difficult Reality to Digest: The Effects of a Corn-Based Diet on the Digestive System of Cattle

A complex system of economic and political policies has led to the mass over production of corn in the United States. As a result of this overproduction, we now see corn in the majority of processed foods as well as animal feeds, in particular cattle feed. However, evolutionarily cattle are adapted to pasture diets not corn-based diets. Cattle have complex digestive systems, consisting of the r...

Absence of TDP-43 is difficult to digest.

It is well established that TDP-43 accumulates in degenerating neurons in patients with ALS/FTLD, which might affect normal TDP-43 function. In this issue of The EMBO Journal Xia et al (2016) show a novel connection between TDP-43 loss of function and autophagy failure. Using knockdown models of TDP-43, they observed enhanced autophagosome and lysosome biogenesis through mTORC1 activity inhibit...

The woman patient after WHI.

An epidemic of fear and distrust has infected women (and physicians) after publication of the Women's Health Initiative (WHI). The overinflated negative data emerging from the oestroprogestinic arm of WHI have frightened women and gave rise to the most difficult emotions to cope with. Keywords such as cancer, death and hormones combined together, have potentiated an avoidant attitude towards ho...

Prevention of Iodine Deficiency: Difficult to Implement, More Difficult to Sustain

Management of the difficult Airway

The appropriate airway management is the important point during the anesthesia. For it dose, ‎taking history, physical examination (head and neck, mandible, mouth opening, neck ‎movements …) must be done completely and they are helpful in estimating difficult ‎intubation.‎ It is necessary to note that one case from every ‎‏5000‏‎ cases of anesthesia, not o...